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A Genome-Wide Immunodetection Screen in S. cerevisiae Uncovers Novel Genes Involved in Lysosomal Vacuole Function and Morphology

Vacuoles of yeast Saccharomyces cerevisiae are functionally analogous to mammalian lysosomes. Both are cellular organelles responsible for macromolecular degradation, ion/pH homeostasis, and stress survival. We hypothesized that undefined gene functions remain at post-endosomal stage of vacuolar eve...

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Detalles Bibliográficos
Autores principales: Ricarte, Florante, Menjivar, Rosa, Chhun, Surya, Soreta, Tattika, Oliveira, Lisa, Hsueh, Teli, Serranilla, Maribeth, Gharakhanian, Editte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166051/
https://www.ncbi.nlm.nih.gov/pubmed/21912603
http://dx.doi.org/10.1371/journal.pone.0023696