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A Positive Role of Cadherin in Wnt/β-Catenin Signalling during Epithelial-Mesenchymal Transition

The Wnt/β-catenin signalling pathway shares a key component, β-catenin, with the cadherin-based adhesion system. The signalling function of β-catenin is conferred by a soluble cytoplasmic pool that is unstable in the absence of a Wnt signal, whilst the adhesion function is based on a cadherin-bound,...

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Detalles Bibliográficos
Autores principales: Howard, Sara, Deroo, Tom, Fujita, Yasuyuki, Itasaki, Nobue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166074/
https://www.ncbi.nlm.nih.gov/pubmed/21909376
http://dx.doi.org/10.1371/journal.pone.0023899