Stressing the Ubiquitin-Proteasome System without 20S Proteolytic Inhibition Selectively Kills Cervical Cancer Cells

Cervical cancer cells exhibit an increased requirement for ubiquitin-dependent protein degradation associated with an elevated metabolic turnover rate, and for specific signaling pathways, notably HPV E6-targeted degradation of p53 and PDZ proteins. Natural compounds with antioxidant properties incl...

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Detalles Bibliográficos
Autores principales: Anchoori, Ravi K., Khan, Saeed R., Sueblinvong, Thanasak, Felthauser, Alicia, Iizuka, Yoshie, Gavioli, Riccardo, Destro, Federica, Isaksson Vogel, Rachel, Peng, Shiwen, Roden, Richard B. S., Bazzaro, Martina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166081/
https://www.ncbi.nlm.nih.gov/pubmed/21909374
http://dx.doi.org/10.1371/journal.pone.0023888

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166081/
https://www.ncbi.nlm.nih.gov/pubmed/21909374
http://dx.doi.org/10.1371/journal.pone.0023888

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