Amyloid Triggers Extensive Cerebral Angiogenesis Causing Blood Brain Barrier Permeability and Hypervascularity in Alzheimer's Disease

Evidence of reduced blood-brain barrier (BBB) integrity preceding other Alzheimer's disease (AD) pathology provides a strong link between cerebrovascular angiopathy and AD. However, the “Vascular hypothesis”, holds that BBB leakiness in AD is likely due to hypoxia and neuroinflammation leading...

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Detalles Bibliográficos
Autores principales: Biron, Kaan E., Dickstein, Dara L., Gopaul, Rayshad, Jefferies, Wilfred A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166122/
https://www.ncbi.nlm.nih.gov/pubmed/21909359
http://dx.doi.org/10.1371/journal.pone.0023789

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166122/
https://www.ncbi.nlm.nih.gov/pubmed/21909359
http://dx.doi.org/10.1371/journal.pone.0023789

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