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Global Analysis of Gene Expression in the Developing Brain of Gtf2ird1 Knockout Mice

BACKGROUND: Williams-Beuren Syndrome (WBS) is a neurodevelopmental disorder caused by a hemizygous deletion of a 1.5 Mb region on chromosome 7q11.23 encompassing 26 genes. One of these genes, GTF2IRD1, codes for a putative transcription factor that is expressed throughout the brain during developmen...

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Detalles Bibliográficos
Autores principales: O'Leary, Jennifer, Osborne, Lucy R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166129/
https://www.ncbi.nlm.nih.gov/pubmed/21909369
http://dx.doi.org/10.1371/journal.pone.0023868