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A Method for Efficient Calculation of Diffusion and Reactions of Lipophilic Compounds in Complex Cell Geometry

A general description of effects of toxic compounds in mammalian cells is facing several problems. Firstly, most toxic compounds are hydrophobic and partition phenomena strongly influence their behaviour. Secondly, cells display considerable heterogeneity regarding the presence, activity and distrib...

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Detalles Bibliográficos
Autores principales: Dreij, Kristian, Chaudhry, Qasim Ali, Jernström, Bengt, Morgenstern, Ralf, Hanke, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166132/
https://www.ncbi.nlm.nih.gov/pubmed/21912588
http://dx.doi.org/10.1371/journal.pone.0023128