Vaccine Platforms Combining Circumsporozoite Protein and Potent Immune Modulators, rEA or EAT-2, Paradoxically Result in Opposing Immune Responses

BACKGROUND: Malaria greatly impacts the health and wellbeing of over half of the world's population. Promising malaria vaccine candidates have attempted to induce adaptive immune responses to Circumsporozoite (CS) protein. Despite the inclusion of potent adjuvants, these vaccines have limited p...

Descripción completa

Detalles Bibliográficos
Autores principales: Schuldt, Nathaniel J., Aldhamen, Yasser A., Appledorn, Daniel M., Seregin, Sergey S., Kousa, Youssef, Godbehere, Sarah, Amalfitano, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166157/
https://www.ncbi.nlm.nih.gov/pubmed/21912619
http://dx.doi.org/10.1371/journal.pone.0024147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166157/
https://www.ncbi.nlm.nih.gov/pubmed/21912619
http://dx.doi.org/10.1371/journal.pone.0024147

Ejemplares similares