A Dual Binding Mode for RhoGTPases in Plexin Signalling

Plexins are cell surface receptors for the semaphorin family of cell guidance cues. The cytoplasmic region comprises a Ras GTPase-activating protein (GAP) domain and a RhoGTPase binding domain. Concomitant binding of extracellular semaphorin and intracellular RhoGTPase triggers GAP activity and sign...

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Detalles Bibliográficos
Autores principales: Bell, Christian H., Aricescu, A. Radu, Jones, E. Yvonne, Siebold, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166162/
https://www.ncbi.nlm.nih.gov/pubmed/21912513
http://dx.doi.org/10.1371/journal.pbio.1001134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166162/
https://www.ncbi.nlm.nih.gov/pubmed/21912513
http://dx.doi.org/10.1371/journal.pbio.1001134

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