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Down-Regulation of NDRG1 Promotes Migration of Cancer Cells during Reoxygenation

One characteristic of tumor microenvironment is oxygen fluctuation, which results from hyper-proliferation and abnormal metabolism of tumor cells as well as disorganized neo-vasculature. Reoxygenation of tumors can induce oxidative stress, which leads to DNA damage and genomic instability. Although...

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Detalles Bibliográficos
Autores principales: Lai, Liang-Chuan, Su, Yi-Yu, Chen, Kuo-Chih, Tsai, Mong-Hsun, Sher, Yuh-Pyng, Lu, Tzu-Pin, Lee, Chien-Yueh, Chuang, Eric Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166165/
https://www.ncbi.nlm.nih.gov/pubmed/21912630
http://dx.doi.org/10.1371/journal.pone.0024375