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Down-Regulation of NDRG1 Promotes Migration of Cancer Cells during Reoxygenation
One characteristic of tumor microenvironment is oxygen fluctuation, which results from hyper-proliferation and abnormal metabolism of tumor cells as well as disorganized neo-vasculature. Reoxygenation of tumors can induce oxidative stress, which leads to DNA damage and genomic instability. Although...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166165/ https://www.ncbi.nlm.nih.gov/pubmed/21912630 http://dx.doi.org/10.1371/journal.pone.0024375 |