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A Recombinant Avian Infectious Bronchitis Virus Expressing a Heterologous Spike Gene Belonging to the 4/91 Serotype

We have shown previously that replacement of the spike (S) gene of the apathogenic IBV strain Beau-R with that from the pathogenic strain of the same serotype, M41, resulted in an apathogenic virus, BeauR-M41(S), that conferred protection against challenge with M41 [1]. We have constructed a recombi...

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Detalles Bibliográficos
Autores principales: Armesto, Maria, Evans, Sharon, Cavanagh, David, Abu-Median, Abu-Bakr, Keep, Sarah, Britton, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166170/
https://www.ncbi.nlm.nih.gov/pubmed/21912629
http://dx.doi.org/10.1371/journal.pone.0024352