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Analyzing the Functional Properties of the Creatine Kinase System with Multiscale ‘Sloppy’ Modeling
In this study the function of the two isoforms of creatine kinase (CK; EC 2.7.3.2) in myocardium is investigated. The ‘phosphocreatine shuttle’ hypothesis states that mitochondrial and cytosolic CK plays a pivotal role in the transport of high-energy phosphate (HEP) groups from mitochondria to myofi...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166207/ https://www.ncbi.nlm.nih.gov/pubmed/21912519 http://dx.doi.org/10.1371/journal.pcbi.1002130 |