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Analyzing the Functional Properties of the Creatine Kinase System with Multiscale ‘Sloppy’ Modeling

In this study the function of the two isoforms of creatine kinase (CK; EC 2.7.3.2) in myocardium is investigated. The ‘phosphocreatine shuttle’ hypothesis states that mitochondrial and cytosolic CK plays a pivotal role in the transport of high-energy phosphate (HEP) groups from mitochondria to myofi...

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Detalles Bibliográficos
Autores principales:	Hettling, Hannes, van Beek, Johannes HGM
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166207/ https://www.ncbi.nlm.nih.gov/pubmed/21912519 http://dx.doi.org/10.1371/journal.pcbi.1002130

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