Telomeres are shortened in acinar-to-ductal metaplasia lesions associated with pancreatic intraepithelial neoplasia but not in isolated acinar-to-ductal metaplasias

Telomeres protect against chromosomal breakage, fusion, and interchromosome bridges during cell division. Shortened telomeres have been observed in the lowest grade of pancreatic intraepithelial neoplasia. Genetically engineered mouse models of pancreatic neoplasia develop acinar-to-ductal metaplasi...

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Detalles Bibliográficos
Autores principales: Hong, Seung-Mo, Heaphy, Christopher M., Shi, Chanjuan, Eo, Soo-Heang, Cho, HyungJun, Meeker, Alan K., Eshleman, James R., Hruban, Ralph H., Goggins, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166222/
https://www.ncbi.nlm.nih.gov/pubmed/20871595
http://dx.doi.org/10.1038/modpathol.2010.181

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166222/
https://www.ncbi.nlm.nih.gov/pubmed/20871595
http://dx.doi.org/10.1038/modpathol.2010.181

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