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Polymorphic variability in the 3' untranslated region (UTR) of IL12B is associated with susceptibility to severe anaemia in Kenyan children with acute Plasmodium falciparum malaria

BACKGROUND: Plasmodium falciparum malaria remains a leading cause of morbidity and mortality among African children. Innate immunity provides the first line of defence against P. falciparum infections, particularly in young children that lack naturally-acquired malarial immunity, such as the populat...

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Detalles Bibliográficos
Autores principales: Ong'echa, John M, Raballah, Evans O, Kempaiah, Prakasha M, Anyona, Samuel B, Were, Tom, Davenport, Gregory C, Konah, Stephen, Vulule, John M, Ouma, Collins, Hittner, James B, Perkins, Douglas J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166270/
https://www.ncbi.nlm.nih.gov/pubmed/21819616
http://dx.doi.org/10.1186/1471-2156-12-69