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Identification of an epigenetic biomarker panel with high sensitivity and specificity for colorectal cancer and adenomas

BACKGROUND: The presence of cancer-specific DNA methylation patterns in epithelial colorectal cells in human feces provides the prospect of a simple, non-invasive screening test for colorectal cancer and its precursor, the adenoma. This study investigates a panel of epigenetic markers for the detect...

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Detalles Bibliográficos
Autores principales: Lind, Guro E, Danielsen, Stine A, Ahlquist, Terje, Merok, Marianne A, Andresen, Kim, Skotheim, Rolf I, Hektoen, Merete, Rognum, Torleiv O, Meling, Gunn I, Hoff, Geir, Bretthauer, Michael, Thiis-Evensen, Espen, Nesbakken, Arild, Lothe, Ragnhild A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166273/
https://www.ncbi.nlm.nih.gov/pubmed/21777459
http://dx.doi.org/10.1186/1476-4598-10-85