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Functional Polymorphism of the Mu-Opioid Receptor Gene (OPRM1) Influences Reinforcement Learning in Humans

Previous reports on the functional effects (i.e., gain or loss of function), and phenotypic outcomes (e.g., changes in addiction vulnerability and stress response) of a commonly occurring functional single nucleotide polymorphism (SNP) of the mu-opioid receptor (OPRM1 A118G) have been inconsistent....

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Detalles Bibliográficos
Autores principales: Lee, Mary R., Gallen, Courtney L., Zhang, Xiaochu, Hodgkinson, Colin A., Goldman, David, Stein, Elliot A., Barr, Christina S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166306/
https://www.ncbi.nlm.nih.gov/pubmed/21912675
http://dx.doi.org/10.1371/journal.pone.0024203