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A Virus-Free Poly-Promoter Vector Induces Pluripotency in Quiescent Bovine Cells under Chemically Defined Conditions of Dual Kinase Inhibition

Authentic induced pluripotent stem cells (iPSCs), capable of giving rise to all cell types of an adult animal, are currently only available in mouse. Here, we report the first generation of bovine iPSC-like cells following transfection with a novel virus-free poly-promoter vector. This vector contai...

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Detalles Bibliográficos
Autores principales: Huang, Ben, Li, Tong, Alonso-Gonzalez, Lucia, Gorre, Ruben, Keatley, Sarah, Green, Andria, Turner, Pavla, Kallingappa, Prasanna Kumar, Verma, Vinod, Oback, Björn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166309/
https://www.ncbi.nlm.nih.gov/pubmed/21912700
http://dx.doi.org/10.1371/journal.pone.0024501