Protection of repetitive DNA borders from self-induced meiotic instability

DNA double strand breaks (DSBs) in repetitive sequences are a potent source of genomic instability, due to the possibility of non-allelic homologous recombination (NAHR). Repetitive sequences are especially at risk during meiosis, when numerous programmed DSBs are introduced into the genome to initi...

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Detalles Bibliográficos
Autores principales: Vader, Gerben, Blitzblau, Hannah G., Tame, Mihoko A., Falk, Jill E., Curtin, Lisa, Hochwagen, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166416/
https://www.ncbi.nlm.nih.gov/pubmed/21822291
http://dx.doi.org/10.1038/nature10331

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166416/
https://www.ncbi.nlm.nih.gov/pubmed/21822291
http://dx.doi.org/10.1038/nature10331

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