Cargando…
Protection of repetitive DNA borders from self-induced meiotic instability
DNA double strand breaks (DSBs) in repetitive sequences are a potent source of genomic instability, due to the possibility of non-allelic homologous recombination (NAHR). Repetitive sequences are especially at risk during meiosis, when numerous programmed DSBs are introduced into the genome to initi...
Autores principales: | Vader, Gerben, Blitzblau, Hannah G., Tame, Mihoko A., Falk, Jill E., Curtin, Lisa, Hochwagen, Andreas |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166416/ https://www.ncbi.nlm.nih.gov/pubmed/21822291 http://dx.doi.org/10.1038/nature10331 |
Ejemplares similares
-
ATR/Mec1 prevents lethal meiotic recombination initiation on partially replicated chromosomes in budding yeast
por: Blitzblau, Hannah G, et al.
Publicado: (2013) -
Separation of DNA Replication from the Assembly of Break-Competent Meiotic Chromosomes
por: Blitzblau, Hannah G., et al.
Publicado: (2012) -
Transcription dynamically patterns the meiotic chromosome-axis interface
por: Sun, Xiaoji, et al.
Publicado: (2015) -
Chromosome Synapsis Alleviates Mek1-Dependent Suppression of Meiotic DNA Repair
por: Subramanian, Vijayalakshmi V., et al.
Publicado: (2016) -
Kinetochores, cohesin, and DNA breaks: Controlling meiotic recombination within pericentromeres
por: Kuhl, Lisa‐Marie, et al.
Publicado: (2019)