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Overexpression of PGC-1α Increases Fatty Acid Oxidative Capacity of Human Skeletal Muscle Cells

We investigated the effects of PGC-1α (peroxisome proliferator-activated receptor γ coactivator-1α) overexpression on the oxidative capacity of human skeletal muscle cells ex vivo. PGC-1α overexpression increased the oxidation rate of palmitic acid and mRNA expression of genes regulating lipid metab...

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Detalles Bibliográficos
Autores principales: Nikolić, Nataša, Rhedin, Magdalena, Rustan, Arild C., Storlien, Len, Thoresen, G. Hege, Strömstedt, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166714/
https://www.ncbi.nlm.nih.gov/pubmed/21904680
http://dx.doi.org/10.1155/2012/714074