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Effects of the Demethylating Agent, 5-Azacytidine, on Expression of the Kallikrein-Kinin Genes in Carcinoma Cells of the Lung and Pleura

Tissue kallikrein (KLK1) and plasma kallikrein (KLKB1) may regulate the growth and proliferation of tumours of the lung and pleura, through the generation of kinin peptides that signal through the kinin B(1) (BDKRB1) and B(2) (BDKRB2) receptors. The development and progression of cancer results from...

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Detalles Bibliográficos
Autores principales: Wong, Joshua, Sia, Yee Yen, Misso, Neil L., Aggarwal, Shashi, Ng, Angeline, Bhoola, Kanti D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166727/
https://www.ncbi.nlm.nih.gov/pubmed/21904690
http://dx.doi.org/10.4061/2011/167046