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4-Hydroxy-2-Nonenal-Modified Glyceraldehyde-3-Phosphate Dehydrogenase Is Degraded by Cathepsin G in Rat Neutrophils

Degradation of oxidized or oxidatively modified proteins is an essential part of the antioxidant defenses of cells. 4-Hydroxy-2-nonenal, a major reactive aldehyde formed by lipid peroxidation, causes many types of cellular damage. It has been reported that 4-hydroxy-2-nonenal-modified proteins are d...

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Detalles Bibliográficos
Autores principales: Tsuchiya, Yukihiro, Okada, Go, Kobayashi, Shigeki, Chikuma, Toshiyuki, Hojo, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166769/
https://www.ncbi.nlm.nih.gov/pubmed/21904640
http://dx.doi.org/10.1155/2011/213686