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Tuberous sclerosis complex and Myc coordinate the growth and division of Drosophila intestinal stem cells

Intestinal stem cells (ISCs) in the adult Drosophila melanogaster midgut can respond to damage and support repair. We demonstrate in this paper that the tuberous sclerosis complex (TSC) plays a critical role in balancing ISC growth and division. Previous studies have shown that imaginal disc cells t...

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Detalles Bibliográficos
Autores principales: Amcheslavsky, Alla, Ito, Naoto, Jiang, Jin, Ip, Y. Tony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166862/
https://www.ncbi.nlm.nih.gov/pubmed/21555458
http://dx.doi.org/10.1083/jcb.201103018