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NPHP4, a cilia-associated protein, negatively regulates the Hippo pathway

The conserved Hippo signaling pathway regulates organ size in Drosophila melanogaster and mammals and has an essential role in tumor suppression and the control of cell proliferation. Recent studies identified activators of Hippo signaling, but antagonists of the pathway have remained largely elusiv...

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Detalles Bibliográficos
Autores principales: Habbig, Sandra, Bartram, Malte P., Müller, Roman U., Schwarz, Ricarda, Andriopoulos, Nikolaos, Chen, Shuhua, Sägmüller, Josef G., Hoehne, Martin, Burst, Volker, Liebau, Max C., Reinhardt, H. Christian, Benzing, Thomas, Schermer, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166863/
https://www.ncbi.nlm.nih.gov/pubmed/21555462
http://dx.doi.org/10.1083/jcb.201009069