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Titin visualization in real time reveals an unexpected level of mobility within and between sarcomeres

The giant muscle protein titin is an essential structural component of the sarcomere. It forms a continuous periodic backbone along the myofiber that provides resistance to mechanical strain. Thus, the titin filament has been regarded as a blueprint for sarcomere assembly and a prerequisite for stab...

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Detalles Bibliográficos
Autores principales: da Silva Lopes, Katharina, Pietas, Agnieszka, Radke, Michael H., Gotthardt, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166869/
https://www.ncbi.nlm.nih.gov/pubmed/21555460
http://dx.doi.org/10.1083/jcb.201010099