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Involvement of mTOR signaling in sphingosylphosphorylcholine-induced hypopigmentation effects

BACKGROUND: Sphingosylphosphorylcholine (SPC) acts as a potent lipid mediator and signaling molecule in various cell types. In the present study, we investigated the effects of SPC on melanogenesis and SPC-modulated signaling pathways related to melanin synthesis. METHODS: Melanin production was mea...

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Detalles Bibliográficos
Autores principales: Jeong, Hyo-Soon, Lee, Seung Hoon, Yun, Hye-Young, Baek, Kwang Jin, Kwon, Nyoun Soo, Park, Kyoung-Chan, Kim, Dong-Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166904/
https://www.ncbi.nlm.nih.gov/pubmed/21838918
http://dx.doi.org/10.1186/1423-0127-18-55