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Attenuation of virulence in an apicomplexan hemoparasite results in reduced genome diversity at the population level

BACKGROUND: Virulence acquisition and loss is a dynamic adaptation of pathogens to thrive in changing milieus. We investigated the mechanisms of virulence loss at the whole genome level using Babesia bovis as a model apicomplexan in which genetically related attenuated parasites can be reliably deri...

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Detalles Bibliográficos
Autores principales: Lau, Audrey OT, Kalyanaraman, Ananth, Echaide, Ignacio, Palmer, Guy H, Bock, Russell, Pedroni, Monica J, Rameshkumar, Meenakshi, Ferreira, Mariano B, Fletcher, Taryn I, McElwain, Terry F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166950/
https://www.ncbi.nlm.nih.gov/pubmed/21838895
http://dx.doi.org/10.1186/1471-2164-12-410