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Attenuation of virulence in an apicomplexan hemoparasite results in reduced genome diversity at the population level
BACKGROUND: Virulence acquisition and loss is a dynamic adaptation of pathogens to thrive in changing milieus. We investigated the mechanisms of virulence loss at the whole genome level using Babesia bovis as a model apicomplexan in which genetically related attenuated parasites can be reliably deri...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166950/ https://www.ncbi.nlm.nih.gov/pubmed/21838895 http://dx.doi.org/10.1186/1471-2164-12-410 |