Renal defects in KCNE1 knockout mice are mimicked by chromanol 293B in vivo: identification of a KCNE1-regulated K(+) conductance in the proximal tubule

ABSTRACT: KCNE1 is a protein of low molecular mass that is known to regulate the chromanol 293B and clofilium-sensitive K(+) channel, KCNQ1, in a number of tissues. Previous work on the kidney of KCNE1 and KCNQ1 knockout mice has revealed that these animals have different renal phenotypes, suggestin...

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Detalles Bibliográficos
Autores principales: Neal, A M, Taylor, H C, Millar, I D, Kibble, J D, White, S J, Robson, L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Science Inc 2011
Materias:
Renal and Endocrine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167120/
https://www.ncbi.nlm.nih.gov/pubmed/21576273
http://dx.doi.org/10.1113/jphysiol.2011.209155

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167120/
https://www.ncbi.nlm.nih.gov/pubmed/21576273
http://dx.doi.org/10.1113/jphysiol.2011.209155

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