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Altered Expression of Somatostatin Receptors in Pancreatic Islets from NOD Mice Cultured at Different Glucose Concentrations In Vitro and in Islets Transplanted to Diabetic NOD Mice In Vivo

Somatostatin acts via five receptors (sst(1–5)). We investigated if the changes in pancreatic islet sst expression in diabetic NOD mice compared to normoglycemic mice are a consequence of hyperglycemia or the ongoing immune reaction in the pancreas. Pancreatic islets were isolated from NOD mice prec...

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Detalles Bibliográficos
Autores principales: Ludvigsen, Eva, Stridsberg, Mats, Janson, Eva T., Sandler, Stellan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167186/
https://www.ncbi.nlm.nih.gov/pubmed/21912536
http://dx.doi.org/10.1155/2011/623472