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Spectral counting assessment of protein dynamic range in cerebrospinal fluid following depletion with plasma-designed immunoaffinity columns

BACKGROUND: In cerebrospinal fluid (CSF), which is a rich source of biomarkers for neurological diseases, identification of biomarkers requires methods that allow reproducible detection of low abundance proteins. It is therefore crucial to decrease dynamic range and improve assessment of protein abu...

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Detalles Bibliográficos
Autores principales: Borg, Jacques, Campos, Alex, Diema, Claudio, Omeñaca, Núria, de Oliveira, Eliandre, Guinovart, Joan, Vilaseca, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167203/
https://www.ncbi.nlm.nih.gov/pubmed/21906361
http://dx.doi.org/10.1186/1559-0275-8-6