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Novel monoclonal antibodies against Pdx1 reveal feedback regulation of Pdx1 protein levels

The aim of this study was to characterize two monoclonal antibodies (F6A11 and F109-D12) generated against Pdx1 (pancreatic and duodenal homeobox-1), a homeodomain transcription factor, which is critical for pancreas formation as well as for normal pancreatic beta cell function. For production of mo...

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Detalles Bibliográficos
Autores principales: Galbo, T., Pedersen, I.L., Fløyel, T., Bang-Berthelsen, C.H., Serup, P., Madsen, O.D., Hald, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167305/
https://www.ncbi.nlm.nih.gov/pubmed/20558340
http://dx.doi.org/10.4081/ejh.2010.e19