Experimental strategies for microRNA target identification

MicroRNAs (miRNAs) are important regulators of eukaryotic gene expression in most biological processes. They act by guiding the RNAi-induced silencing complex (RISC) to partially complementary sequences in target mRNAs to suppress gene expression by a combination of translation inhibition and mRNA d...

Descripción completa

Detalles Bibliográficos
Autores principales: Thomson, Daniel W., Bracken, Cameron P., Goodall, Gregory J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167600/
https://www.ncbi.nlm.nih.gov/pubmed/21652644
http://dx.doi.org/10.1093/nar/gkr330