Endogenously induced DNA double strand breaks arise in heterochromatic DNA regions and require ataxia telangiectasia mutated and Artemis for their repair

Ataxia telangiectasia (ATM) mutated and Artemis, the proteins defective in ataxia telangiectasia and a class of Radiosensitive-Severe Combined Immunodeficiency (RS-SCID), respectively, function in the repair of DNA double strand breaks (DSBs), which arise in heterochromatic DNA (HC-DSBs) following e...

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Detalles Bibliográficos
Autores principales: Woodbine, Lisa, Brunton, H., Goodarzi, A. A., Shibata, A., Jeggo, P. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167608/
https://www.ncbi.nlm.nih.gov/pubmed/21596788
http://dx.doi.org/10.1093/nar/gkr331

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167608/
https://www.ncbi.nlm.nih.gov/pubmed/21596788
http://dx.doi.org/10.1093/nar/gkr331

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