Cargando…

Endogenously induced DNA double strand breaks arise in heterochromatic DNA regions and require ataxia telangiectasia mutated and Artemis for their repair

Ataxia telangiectasia (ATM) mutated and Artemis, the proteins defective in ataxia telangiectasia and a class of Radiosensitive-Severe Combined Immunodeficiency (RS-SCID), respectively, function in the repair of DNA double strand breaks (DSBs), which arise in heterochromatic DNA (HC-DSBs) following e...

Descripción completa

Detalles Bibliográficos
Autores principales:	Woodbine, Lisa, Brunton, H., Goodarzi, A. A., Shibata, A., Jeggo, P. A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2011
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167608/ https://www.ncbi.nlm.nih.gov/pubmed/21596788 http://dx.doi.org/10.1093/nar/gkr331

Ejemplares similares

TDP1 suppresses mis-joining of radiomimetic DNA double-strand breaks and cooperates with Artemis to promote optimal nonhomologous end joining
por: Kawale, Ajinkya S, et al.
Publicado: (2018)

XLF-Cernunnos promotes DNA ligase IV–XRCC4 re-adenylation following ligation
por: Riballo, Enriqueta, et al.
Publicado: (2009)

Radiation-induced double-strand breaks require ATM but not Artemis for homologous recombination during S-phase
por: Köcher, Sabrina, et al.
Publicado: (2012)

Translesion DNA synthesis-assisted non-homologous end-joining of complex double-strand breaks prevents loss of DNA sequences in mammalian cells
por: Covo, Shay, et al.
Publicado: (2009)

DNA ligase III acts as a DNA strand break sensor in the cellular orchestration of DNA strand break repair
por: Abdou, Ismail, et al.
Publicado: (2015)

Restoration of G1 chemo/radioresistance and double-strand-break repair proficiency by wild-type but not endonuclease-deficient Artemis
por: Mohapatra, Susovan, et al.
Publicado: (2011)

Pathological mutations in PNKP trigger defects in DNA single-strand break repair but not DNA double-strand break repair
por: Kalasova, Ilona, et al.
Publicado: (2020)

Dna2 initiates resection at clean DNA double-strand breaks
por: Paudyal, Sharad C., et al.
Publicado: (2017)

The Heterochromatic Barrier to DNA Double Strand Break Repair: How to Get the Entry Visa
por: Goodarzi, Aaron A., et al.
Publicado: (2012)

Physical ARTEMIS:DNA-PKcs interaction is necessary for V(D)J recombination
por: Niewolik, Doris, et al.
Publicado: (2022)

Hedgehog signaling enables repair of ribosomal DNA double-strand breaks
por: Lama-Sherpa, Tshering D, et al.
Publicado: (2020)

Phosphorylation of polynucleotide kinase/ phosphatase by DNA-dependent protein kinase and ataxia-telangiectasia mutated regulates its association with sites of DNA damage
por: Zolner, Angela E., et al.
Publicado: (2011)

PHF2 regulates homology-directed DNA repair by controlling the resection of DNA double strand breaks
por: Alonso-de Vega, Ignacio, et al.
Publicado: (2020)

The COP9 signalosome is vital for timely repair of DNA double-strand breaks
por: Meir, Michal, et al.
Publicado: (2015)

ARF induction in response to DNA strand breaks is regulated by PARP1
por: Orlando, Giulia, et al.
Publicado: (2014)

APE1 senses DNA single-strand breaks for repair and signaling
por: Lin, Yunfeng, et al.
Publicado: (2020)

DNA polymerase θ-mediated repair of high LET radiation-induced complex DNA double-strand breaks
por: Yi, Geunil, et al.
Publicado: (2023)

Loss of DNA ligase IV prevents recognition of DNA by double-strand break repair proteins XRCC4 and XLF
por: Jayaram, Sumithra, et al.
Publicado: (2008)

Single-stranded DNA oligomers stimulate error-prone alternative repair of DNA double-strand breaks through hijacking Ku protein
por: Yuan, Ying, et al.
Publicado: (2015)

Mechanistic analysis of Xenopus EXO1's function in 5′-strand resection at DNA double-strand breaks
por: Liao, Shuren, et al.
Publicado: (2011)

p21 promotes error-free replication-coupled DNA double-strand break repair
por: Mauro, Maurizio, et al.
Publicado: (2012)

UVA-induced DNA double-strand breaks result from the repair of clustered oxidative DNA damages
por: Greinert, R., et al.
Publicado: (2012)

DNA double-strand breaks with 5′ adducts are efficiently channeled to the DNA2-mediated resection pathway
por: Tammaro, Margaret, et al.
Publicado: (2016)

Poly(ADP-ribose) polymerases covalently modify strand break termini in DNA fragments in vitro
por: Talhaoui, Ibtissam, et al.
Publicado: (2016)

A moonlighting metabolic protein influences repair at DNA double-stranded breaks
por: Torres-Machorro, Ana Lilia, et al.
Publicado: (2015)

Evidence for double-strand break mediated mitochondrial DNA replication in Saccharomyces cerevisiae
por: Prasai, Kanchanjunga, et al.
Publicado: (2017)

Topoisomerase II contributes to DNA secondary structure-mediated double-stranded breaks
por: Szlachta, Karol, et al.
Publicado: (2020)

Human RECQ5 helicase promotes repair of DNA double-strand breaks by synthesis-dependent strand annealing
por: Paliwal, Shreya, et al.
Publicado: (2014)

Cohesin promotes the repair of ionizing radiation-induced DNA double-strand breaks in replicated chromatin
por: Bauerschmidt, Christina, et al.
Publicado: (2010)

DNA-PK(cs)-dependent phosphorylation of RECQL4 promotes NHEJ by stabilizing the NHEJ machinery at DNA double-strand breaks
por: Lu, Huiming, et al.
Publicado: (2022)

RNA–DNA hybrids promote the expansion of Friedreich's ataxia (GAA)(n) repeats via break-induced replication
por: Neil, Alexander J, et al.
Publicado: (2018)

Secondary structure forming sequences drive SD-MMEJ repair of DNA double-strand breaks
por: Khodaverdian, Varandt Y., et al.
Publicado: (2017)

PARP activation regulates the RNA-binding protein NONO in the DNA damage response to DNA double-strand breaks
por: Krietsch, Jana, et al.
Publicado: (2012)

ATM antagonizes NHEJ proteins assembly and DNA-ends synapsis at single-ended DNA double strand breaks
por: Britton, Sébastien, et al.
Publicado: (2020)

Bridging of double-stranded breaks by the nonhomologous end-joining ligation complex is modulated by DNA end chemistry
por: Reid, Dylan A., et al.
Publicado: (2017)

Phosphorylation of Exo1 modulates homologous recombination repair of DNA double-strand breaks
por: Bolderson, Emma, et al.
Publicado: (2010)

Cellular responses to DNA double-strand breaks after low-dose γ-irradiation
por: Asaithamby, Aroumougame, et al.
Publicado: (2009)

Analysis of MRE11's function in the 5′→3′ processing of DNA double-strand breaks
por: Liao, Shuren, et al.
Publicado: (2012)

The 9-1-1 checkpoint clamp coordinates resection at DNA double strand breaks
por: Ngo, Greg H.P., et al.
Publicado: (2015)

Processing by MRE11 is involved in the sensitivity of subtelomeric regions to DNA double-strand breaks
por: Muraki, Keiko, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_ndmhqmkki85p48l26n350fkfa0