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Quadruplex formation is necessary for stable PNA invasion into duplex DNA of BCL2 promoter region
Guanine-rich sequences are highly abundant in the human genome, especially in regulatory regions. Because guanine-rich sequences have the unique ability to form G-quadruplexes, these structures may play a role in the regulation of gene transcription. In previous studies, we demonstrated that formati...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167611/ https://www.ncbi.nlm.nih.gov/pubmed/21593130 http://dx.doi.org/10.1093/nar/gkr259 |