UV stalled replication forks restart by re-priming in human fibroblasts

Restarting stalled replication forks is vital to avoid fatal replication errors. Previously, it was demonstrated that hydroxyurea-stalled replication forks rescue replication either by an active restart mechanism or by new origin firing. To our surprise, using the DNA fibre assay, we only detect a s...

Descripción completa

Detalles Bibliográficos
Autores principales: Elvers, Ingegerd, Johansson, Fredrik, Groth, Petra, Erixon, Klaus, Helleday, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167624/
https://www.ncbi.nlm.nih.gov/pubmed/21646340
http://dx.doi.org/10.1093/nar/gkr420

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167624/
https://www.ncbi.nlm.nih.gov/pubmed/21646340
http://dx.doi.org/10.1093/nar/gkr420

Ejemplares similares