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UV stalled replication forks restart by re-priming in human fibroblasts

Restarting stalled replication forks is vital to avoid fatal replication errors. Previously, it was demonstrated that hydroxyurea-stalled replication forks rescue replication either by an active restart mechanism or by new origin firing. To our surprise, using the DNA fibre assay, we only detect a s...

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Detalles Bibliográficos
Autores principales:	Elvers, Ingegerd, Johansson, Fredrik, Groth, Petra, Erixon, Klaus, Helleday, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2011
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167624/ https://www.ncbi.nlm.nih.gov/pubmed/21646340 http://dx.doi.org/10.1093/nar/gkr420

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