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Cross-linking of DNA through HMGA1 suggests a DNA scaffold

Binding of proteins to DNA is usually considered 1D with one protein bound to one DNA molecule. In principle, proteins with multiple DNA binding domains could also bind to and thereby cross-link different DNA molecules. We have investigated this possibility using high-mobility group A1 (HMGA1) prote...

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Detalles Bibliográficos
Autores principales: Vogel, Benjamin, Löschberger, Anna, Sauer, Markus, Hock, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167630/
https://www.ncbi.nlm.nih.gov/pubmed/21596776
http://dx.doi.org/10.1093/nar/gkr396