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Reciprocal roles of DBC1 and SIRT1 in regulating estrogen receptor α activity and co-activator synergy
Estrogen receptor α (ERα) plays critical roles in development and progression of breast cancer. Because ERα activity is strictly dependent upon the interaction with coregulators, coregulators are also believed to contribute to breast tumorigenesis. Cell Cycle and Apoptosis Regulator 1 (CCAR1) is an...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167635/ https://www.ncbi.nlm.nih.gov/pubmed/21596782 http://dx.doi.org/10.1093/nar/gkr347 |