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Reciprocal roles of DBC1 and SIRT1 in regulating estrogen receptor α activity and co-activator synergy

Estrogen receptor α (ERα) plays critical roles in development and progression of breast cancer. Because ERα activity is strictly dependent upon the interaction with coregulators, coregulators are also believed to contribute to breast tumorigenesis. Cell Cycle and Apoptosis Regulator 1 (CCAR1) is an...

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Detalles Bibliográficos
Autores principales: Ji Yu, Eun, Kim, Seok-Hyung, Heo, Kyu, Ou, Chen-Yin, Stallcup, Michael R., Kim, Jeong Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167635/
https://www.ncbi.nlm.nih.gov/pubmed/21596782
http://dx.doi.org/10.1093/nar/gkr347