The distinctive roles of erythroid specific activator GATA-1 and NF-E2 in transcription of the human fetal γ-globin genes

GATA-1 and NF-E2 are erythroid specific activators that bind to the β-globin locus. To explore the roles of these activators in transcription of the human fetal stage specific γ-globin genes, we reduced GATA-1 and p45/NF-E2 using shRNA in erythroid K562 cells. GATA-1 or p45/NF-E2 knockdown inhibited...

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Detalles Bibliográficos
Autores principales: Woon Kim, Yea, Kim, Seoyeon, Geun Kim, Chul, Kim, AeRi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167640/
https://www.ncbi.nlm.nih.gov/pubmed/21609963
http://dx.doi.org/10.1093/nar/gkr253

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167640/
https://www.ncbi.nlm.nih.gov/pubmed/21609963
http://dx.doi.org/10.1093/nar/gkr253

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