How and when should interactome-derived clusters be used to predict functional modules and protein function?

Motivation: Clustering of protein–protein interaction networks is one of the most common approaches for predicting functional modules, protein complexes and protein functions. But, how well does clustering perform at these tasks? Results: We develop a general framework to assess how well computation...

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Detalles Bibliográficos
Autores principales: Song, Jimin, Singh, Mona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167697/
https://www.ncbi.nlm.nih.gov/pubmed/19770263
http://dx.doi.org/10.1093/bioinformatics/btp551

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167697/
https://www.ncbi.nlm.nih.gov/pubmed/19770263
http://dx.doi.org/10.1093/bioinformatics/btp551

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