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Extended passaging increases the efficiency of neural differentiation from induced pluripotent stem cells

BACKGROUND: The use of induced pluripotent stem cells (iPSCs) for the functional replacement of damaged neurons and in vitro disease modeling is of great clinical relevance. Unfortunately, the capacity of iPSC lines to differentiate into neurons is highly variable, prompting the need for a reliable...

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Detalles Bibliográficos
Autores principales: Koehler, Karl R, Tropel, Philippe, Theile, Jonathan W, Kondo, Takako, Cummins, Theodore R, Viville, Stéphane, Hashino, Eri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167757/
https://www.ncbi.nlm.nih.gov/pubmed/21831300
http://dx.doi.org/10.1186/1471-2202-12-82