Cargando…
Extended passaging increases the efficiency of neural differentiation from induced pluripotent stem cells
BACKGROUND: The use of induced pluripotent stem cells (iPSCs) for the functional replacement of damaged neurons and in vitro disease modeling is of great clinical relevance. Unfortunately, the capacity of iPSC lines to differentiate into neurons is highly variable, prompting the need for a reliable...
Autores principales: | Koehler, Karl R, Tropel, Philippe, Theile, Jonathan W, Kondo, Takako, Cummins, Theodore R, Viville, Stéphane, Hashino, Eri |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167757/ https://www.ncbi.nlm.nih.gov/pubmed/21831300 http://dx.doi.org/10.1186/1471-2202-12-82 |
Ejemplares similares
-
Generation of inner ear sensory epithelia from pluripotent stem cells in 3D culture
por: Koehler, Karl R., et al.
Publicado: (2013) -
Generation of inner ear organoids with functional hair cells from human pluripotent stem cells
por: Koehler, Karl R., et al.
Publicado: (2017) -
Random Mutagenesis, Clonal Events, and Embryonic or Somatic Origin Determine the mtDNA Variant Type and Load in Human Pluripotent Stem Cells
por: Zambelli, Filippo, et al.
Publicado: (2018) -
Progress in Modeling and Targeting Inner Ear Disorders with Pluripotent Stem Cells
por: Tang, Pei-Ciao, et al.
Publicado: (2020) -
Neurons and cardiomyocytes derived from induced pluripotent stem cells as a model for mitochondrial defects in Friedreich’s ataxia
por: Hick, Aurore, et al.
Publicado: (2013)