Cargando…

Statistical methodology for the evaluation of vaccine efficacy in a phase III multi-centre trial of the RTS,S/AS01 malaria vaccine in African children

BACKGROUND: There has been much debate about the appropriate statistical methodology for the evaluation of malaria field studies and the challenges in interpreting data arising from these trials. METHODS: The present paper describes, for a pivotal phase III efficacy of the RTS, S/AS01 malaria vaccin...

Descripción completa

Detalles Bibliográficos
Autores principales: Lievens, Marc, Aponte, John J, Williamson, John, Mmbando, Bruno, Mohamed, Ali, Bejon, Philip, Leach, Amanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167766/
https://www.ncbi.nlm.nih.gov/pubmed/21816030
http://dx.doi.org/10.1186/1475-2875-10-222