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In Silico Analysis of Six Known Leishmania major Antigens and In Vitro Evaluation of Specific Epitopes Eliciting HLA-A2 Restricted CD8 T Cell Response

BACKGROUND: As a potent CD8(+) T cell activator, peptide vaccine has found its way in vaccine development against intracellular infections and cancer, but not against leishmaniasis. The first step toward a peptide vaccine is epitope mapping of different proteins according to the most frequent HLA ty...

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Detalles Bibliográficos
Autores principales: Seyed, Negar, Zahedifard, Farnaz, Safaiyan, Shima, Gholami, Elham, Doustdari, Fatemeh, Azadmanesh, Kayhan, Mirzaei, Maryam, Saeedi Eslami, Nasir, Khadem Sadegh, Akbar, Eslami far, Ali, Sharifi, Iraj, Rafati, Sima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167772/
https://www.ncbi.nlm.nih.gov/pubmed/21909442
http://dx.doi.org/10.1371/journal.pntd.0001295