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A novel transferrin receptor-targeted hybrid peptide disintegrates cancer cell membrane to induce rapid killing of cancer cells

BACKGROUND: Transferrin receptor (TfR) is a cell membrane-associated glycoprotein involved in the cellular uptake of iron and the regulation of cell growth. Recent studies have shown the elevated expression levels of TfR on cancer cells compared with normal cells. The elevated expression levels of t...

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Detalles Bibliográficos
Autores principales: Kawamoto, Megumi, Horibe, Tomohisa, Kohno, Masayuki, Kawakami, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167775/
https://www.ncbi.nlm.nih.gov/pubmed/21849092
http://dx.doi.org/10.1186/1471-2407-11-359