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Meningococcal Factor H Binding Proteins in Epidemic Strains from Africa: Implications for Vaccine Development

BACKGROUND: Factor H binding protein (fHbp) is an important antigen for vaccines against meningococcal serogroup B disease. The protein binds human factor H (fH), which enables the bacteria to resist serum bactericidal activity. Little is known about the vaccine-potential of fHbp for control of meni...

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Detalles Bibliográficos
Autores principales: Pajon, Rolando, Fergus, Andrew M., Koeberling, Oliver, Caugant, Dominique A., Granoff, Dan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167780/
https://www.ncbi.nlm.nih.gov/pubmed/21909444
http://dx.doi.org/10.1371/journal.pntd.0001302