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Meningococcal Factor H Binding Proteins in Epidemic Strains from Africa: Implications for Vaccine Development
BACKGROUND: Factor H binding protein (fHbp) is an important antigen for vaccines against meningococcal serogroup B disease. The protein binds human factor H (fH), which enables the bacteria to resist serum bactericidal activity. Little is known about the vaccine-potential of fHbp for control of meni...
Autores principales: | Pajon, Rolando, Fergus, Andrew M., Koeberling, Oliver, Caugant, Dominique A., Granoff, Dan M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167780/ https://www.ncbi.nlm.nih.gov/pubmed/21909444 http://dx.doi.org/10.1371/journal.pntd.0001302 |
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